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Research Paper Discussed in this Talk
Vale RD, Schnapp BJ, Reese TS, Sheetz MP. Organelle, bead, and microtubule translocations promoted by soluble factors from the squid giant axon. Cell. 1985
Mar; 40(3): 559-69.
Educator Resources (Educators only)
These questions and answers were designed to link the iBiology video to the research paper and for use as a classroom activity.
About this Talk
Vale explains how doing science often follows a winding path with unexpected, sometimes wonderful surprises, and uses his own story to illustrate his point. When Vale was a graduate student, he initially hoped to show that myosin was involved in axonal transport, but ended up discovering a new molecule, which he called kinesin.
This video is located in: iBioMagazine Issue 1
About the Speaker
- Ron Vale iBioEducation Lecture: Molecular Motors
- Margaret Gardel iBioMagazine: What is Cytoplasm
- Hugh Huxley iBioEducation Discovery Talk: How Muscle Contracts
- Gary Borisy & Edwin Taylor iBioEducation Discovery Talk: The Discovery of Tubulin
- Research Article: Vale RD, Schnapp BJ, Reese TS, Sheetz MP. Movement of organelles along filaments dissociated from the axoplasm of the squid giant axon. Cell. 1985 Feb;40(2): 449-54.