While working together as junior faculty at the European Molecular Biology Laboratory (EMBL) from 1978 to 1981, Christiane Nüsslein-Volhard and Eric Wieschaus made groundbreaking discoveries about how genes control development in fruitflies. In this interview, Nobel Laureates Nüsslein-Volhard and Wieschaus reminisce about their early experiments, successful collaboration, and what it was like to work in a field in which very little was known at the time.
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About the Speaker
Christiane Nüsslein-Volhard is the Director of Genetics at the Max Planck Institute for Developmental Biology. Throughout her career, Nüsslein-Volhard has studied the genetic basis of development and morphological variation using Drosophila and zebrafish as model systems. She was awarded the 1991 Albert Lasker Award for Basic Medical Research. Eric Wieschaus is the Squibb Professor in Molecular Biology at Princeton University and a Howard Hughes Medical Institute Investigator. Wieschaus has spent his career studying the genes that control early development in Drosophila. Nüsslein-Volhard and Wieschaus were honored with the Nobel Prize in Physiology or Medicine in 1995 for their research.
- Eric Wieschaus iBioMagazine: Finding Genes that Control Development (In this talk, he describes the experiments that led to their discovery)
- Michael Levine iBioSeminar: Transcriptional Precision in the Drosophila Embryo
- Trudi Schupbach iBioSeminar: Control of Embryonic Axis Formation in Drosophila
- Eric Wieschaus iBioSeminar: Patterning Development in the Early Embryo