Jennifer Lippincott-Schwartz explores the function of lipids in regulating the secretory pathway, the steps by which newly synthesized proteins are processed and shuttled from the endoplasmic reticulum to the Golgi to the plasma membrane. The composition of membrane lipids changes across these three main compartments. How is the lipid gradient generated, and does it play a role in protein trafficking and membrane organization?
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About the Speaker
Jennifer Lippincott-Schwartz is Distinguished Investigator and Chief of the Section on Organelle Biology in the Cell Biology and Metabolism Branch at the National Institutes of Health. Lippincott-Schwartz helped pioneer the field of nano-scale resolution microscopy for the visualization of proteins inside living cells. She continues to use live-cell imaging to investigate the dynamics of membrane trafficking, sorting, and compartmentalization in the secretory pathway of eukaryotic cells. In recognition of her scientific contributions, she was elected to the National Academy of Sciences in 2008.
- Jennifer Lippincott-Schwartz iBioSeminar: Breakthroughs in Intracellular Fluorescent Imaging
- Randy Schekman iBioSeminar: Protein Secretion and Vesicle Trafficking
- Randy Schekman iBioEducation: Mysterious Membranes
- Randy Schekman & James Rothman iBioMagazine: Uncovering the Secretory Pathway
- Thomas Reese iBioMagazine: Visualizing Synaptic Signaling
- Kai Simons iBioSeminar: Lipids as Organizers in Cell Membranes
- Satyajit Mayor iBioSeminar: Membrane Rafts
- Youreka Science: The cell's radar: how cells sense their environment