Part II: Hebb’s Postulate Revisited
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In part 1 of his lecture, Dr. Poo gives an overview of the cellular basis of learning and memory. He explains how sensory input results in neuronal activity in the neural circuits that can strengthen or weaken synaptic junctions for extended periods of time. The result of this modification of the synapse is perceptual learning and memory. He describes Donald Hebb’s cell assembly hypothesis that can be summed up as “cells that fire together wire together”. Poo goes on to describe how the phenomenon of long-term potentiation of synapses provides support to the Hebb’s hypothesis.
Currently, Poo is the Paul Licht Distinguished Professor in Biology in the Division of Neurobiology, Department of Molecular and Cell Biology at the University of California, Berkeley. Poo is also founding Director of the Institute of Neuroscience at the Chinese Academy of Sciences since 1999.
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