Zhuang begins her lecture by explaining that the resolution of traditional light microscopy is about 200 nm due to the diffraction of light. This diffraction limit has long hampered the ability of scientists to visualize individual proteins and sub-cellular structures. Xiaowei Zhuang discusses how sub-diffraction limit, or super-resolution, microscopy techniques, such as STORM, allow scientists to obtain images with greater resolution and to study cell dynamics in greater detail.
Xiaowei Zhuang is Professor of Chemistry and Chemical Biology, and Professor of Physics at Harvard University and a Howard Hughes Medical Institute Investigator. She received her B.S. in physics from University of Science and Technology of China and her Ph.D. in physics from the University of California, Berkeley. As a post-doctoral fellow with Steven Chu… Continue Reading
Feather Ives says
Can you add this to the iBiology microscopy series: https://www.ibiology.org/biophysics/super-resolution/