The fat layer in our skin has the ability to expand and shrink. Yet, the regulatory mechanisms for skin fat growth and shrinking are not well understood. In this Share Your Research Talk, Edriss Yousuf describes his thesis research on the regulation of skin fat. He discovered a non-immune function of regulatory T cells and showed that they can induce autophagy in skin fat cells to decrease their lipid droplet size. These findings have implications for scarring and scleroderma, disorders which are typically associated with reduced skin fat abundance.
Edriss Yousuf is a PhD candidate at the Institute for Stem Cell Science and Regenerative Medicine in Bangalore, India, in the laboratory of Colin Jamora. His thesis research led to the discovery of potential therapeutics that can help prevent scarring of skin after wounding or progressive scarring during autoimmune diseases. Edriss seeks to become a… Continue Reading