|Download:||This Video Subtitled Videos: EnglishSpanish|
|Trouble Viewing? Try it on iTunes.Report a problem.|
Research Paper Discussed in this Talk
Capecchi MR. (2005). Gene targeting in mice: functional analysis of the mammalian genome for the twenty-first century. Nat Rev Genet, Jun;6(6):507-12. Review.
Educator Resources (Educators only)
These questions and answers were designed to link the iBiology video to the research paper and for use as a classroom activity.
Prepared by Dr.Yi Liu.
About this Talk
If you strongly believe in an idea, sometimes you need to take some risks to pursue it. This is part of Dr. Capecchi’s message as he describes the challenges in developing the technique of gene targeting from tissue culture cells to mice.
This video is located in: iBioMagazine Issue 3
About the Speaker
Dr. Capecchi is Distinguished Professor of Human Genetics and Biology at the University of Utah and a Howard Hughes Medical Institute Investigator. He is best known for his work on the development of gene targeting in mouse embryonic stem cells. Capecchi was awarded the 2007 Nobel Prize for Medicine or Physiology, with Oliver Smithies and Martin Evans, for his contributions to this field.
- Matthew Meselson iBioEducation Discovery Talk: The Semi-Conservative Replication of DNA
- Paul Berg iBioMagazine: Recombinant DNA and Science Policy
- Tom Cech iBioEducation Discovery Talk: Discovering Ribozymes