Steitz’ story begins in 1977 when introns, exons and RNA splicing had just been discovered. She goes on to tell us of the importance of serendipity in her lab’s discovery of SNURPS, the small nuclear ribonucleoproteins that are key to the splicing of pre-messenger RNA.
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Research Paper Discussed in this Talk
Yang V.W., Lerner M.R., Steitz J.A., and Flint S.J. (1981) A small nuclear ribonucleoprotein is required for splicing of adenoviral early RNA sequences. PNAS, 78, 1371-75.
Educator Resources (Educators only)
These questions and answers were designed to link the iBiology video to the research paper and for use as a classroom activity.
Prepared by Dr. Kassandra Ori-McKenney.
About the Speaker
Joan Steitz is a professor at the Yale School of Medicine, an investigator of the Howard Hughes Medical Institute and a member of the National Academy of Sciences. Steitz continues to study RNA splicing and her lab has identified several other types of RNPs. While Steitz’ science is renowned, she is also applauded for her mentoring and teaching skills
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