Vale explains how doing science often follows a winding path with unexpected, sometimes wonderful surprises, and uses his own story to illustrate his point. When Vale was a graduate student, he initially hoped to show that myosin was involved in axonal transport, but ended up discovering a new molecule which he called kinesin.
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Research Paper Discussed in this Talk
Vale RD, Schnapp BJ, Reese TS, Sheetz MP. Organelle, bead, and microtubule translocations promoted by soluble factors from the squid giant axon. Cell. 1985
Mar; 40(3): 559-69.
Educator Resources (Educators only)
These questions and answers were designed to link the iBiology video to the research paper and for use as a classroom activity.
About the Speaker
Ron Vale is a Professor at the University of California, San Francisco, a Howard Hughes Medical Institute Investigator, and a member of the National Academy of Sciences. He has a long-standing interest in intracellular movement and his lab uses many types of microscopy to study this problem. Vale also founded the iBiology program.
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