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Home » Speakers » Brian Druker
Brian Druker

Brian Druker

Oregon Health & Science University & Howard Hughes Medical Institute
Lasker Award National Academy of Sciences

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Dr. Brian Druker is an Investigator of the Howard Hughes Medical Institute, Director of the Oregon Health & Science University (OHSU) Cancer Institute, and JELD-WEN Chair of Leukemia Research at OHSU. Upon graduating from the University of California, San Diego School of Medicine in 1981, Dr. Druker completed his internship and residency in internal medicine at Barnes Hospital, Washington School of Medicine in St. Louis, Missouri. He then trained in oncology at Harvard’s Dana-Farber Cancer Institute.

Dr. Druker then returned to the lab to begin his research career studying the regulation of the growth of cancer cells and the practical application to cancer therapies. His work was instrumental in the development of Gleevec (imatinib), a drug that targets the molecular defect in chronic myeloid leukemia (CML). After completing a series of preclinical studies, Dr. Druker spearheaded the highly successful clinical trials of imatinib for CML. Imatinib is currently FDA approved for CML and gastrointestinal stromal tumors (GIST). His role in the development of imatinib and its application in the clinic have resulted in numerous awards for Dr. Druker, including Warren Alpert Prize from Harvard Medical School, the American Society of Hematology’s Dameshek Prize, the American Cancer Society’s Medal of Honor, the Kettering Prize from General Motors Cancer Research Foundation, and the David A. Karnofsky Award from the American Society of Clinical Oncology. He was elected to the Institute of Medicine of the National Academies in 2003, the American Association of Physicians in 2006, and the National Academy of Sciences in 2007.

Talks with this Speaker

Imatinib as a Paradigm of Targeted Cancer Therapies

Brian Druker discusses development of Imatinib (Gleevec), a highly successful drug for treatment of chronic myeloid leukemia (CML). (Talk recorded in March 2007)

  • Part 1: Imatinib (Gleevec): A Targeted Cancer Therapy
    Part 1: Imatinib (Gleevec): A Targeted Cancer Therapy
    Audience:
    • Researcher
    • Educators of Adv. Undergrad / Grad
    Duration: 33:54
  • Part 2: Imatinib Resistance and Other Diseases Targeted by Imatinib
    Part 2: Imatinib Resistance and Other Diseases Targeted by Imatinib
    Audience:
    • Researcher
    • Educators of Adv. Undergrad / Grad
    Duration: 25:12
  • Part 3: Extending the Imatinib Paradigm
    Part 3: Extending the Imatinib Paradigm
    Audience:
    • Researcher
    • Educators of Adv. Undergrad / Grad
    Duration: 22:09

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This material is based upon work supported by the National Science Foundation and the National Institute of General Medical Sciences under Grant No. MCB-1052331. Any opinion, finding, conclusion, or recommendation expressed in these videos are solely those of the speaker and do not necessarily represent the views of iBiology, the National Science Foundation, the National Institutes of Health, or other iBiology funders.

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