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Home » Speakers » Christopher E. Rudd
Chris Rudd

Christopher E. Rudd

Université de Montréal

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Christopher E. Rudd, Ph.D. is a professor of medicine at the Université de Montréal where his research focuses on deciphering the signal transduction pathways in T-cells, and how these pathways control immune functions. He received his BSc from McGill University (Canada) and his Ph.D. and D.Sc. degrees from University College London (UK).  Rudd began his studies on T-cell signaling while a faculty member at the Dana-Farber Cancer Institute (DFCI)/Harvard Medical School for 18 years in Boston and then later as a Professor at Cambridge University (UK). 

His laboratory is credited with the discovery of the CD4 and CD8-p56lck complexes that initiate T-cell activation and a phosphorylation cascade involving key downstream targets. The CD4 and CD8-p56lck complexes initiate and broaden T-cell responses to most infectious agents. The discovery also provided a function for src kinases in normal receptor mediated signaling. Further, his work defined key aspects of CD28, ICOS and CTLA-4 co-receptor signaling in T-cells for co-stimulation and immunity. Overall, his research helps to uncover the signaling events that control the adaptive immune response and laid the foundation for therapeutics such as chimeric antigen receptors (CARs) for the treatment of infection, autoimmunity, and cancer. 

In recognition of his work, he has been elected Fellow of the Royal College of Pathologists (2002), the Academy of Medical Sciences (2002) and the Royal Society of Canada (2021). Visit Rudd’s lab website: https://www.christopher-rudd-lab-montreal.com. 

Talks with this Speaker

Pieces of a Puzzle: T Cell Activation

Researchers are harnessing the power of the human immune system to create new treatments for diseases such as cancer. In this video, meet Christopher Rudd, Ph.D., a scientist whose seminal immunology experiments led to the development of cancer immunotherapies. (Talk recorded in November 2021)

Pieces of a Puzzle
Audience:
  • Student
  • Researcher
  • Educators
  • Educators of Adv. Undergrad / Grad
Duration: 00:15:14

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This material is based upon work supported by the National Science Foundation and the National Institute of General Medical Sciences under Grant No. 2122350 and 1 R25 GM139147. Any opinion, finding, conclusion, or recommendation expressed in these videos are solely those of the speakers and do not necessarily represent the views of the Science Communication Lab/iBiology, the National Science Foundation, the National Institutes of Health, or other Science Communication Lab funders.

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