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Home » Speakers » Diane Mathis
Diane Mathis

Diane Mathis

Harvard University

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Diane Mathis is a Professor in the Division of Immunology and the Department of Microbiology and Immunobiology at Harvard Medical School.  She is also a principal member of the Harvard Stem Cell Institute and an associate member of the Broad Institute. Mathis’ lab studies the genetic, cellular and molecular mechanisms that determine immunological tolerance, and autoimmune diseases such as type-1 diabetes and autoimmune polyglandular syndrome that result when immunological self-tolerance fails.  The lab focuses particularly on T cell tolerance. Learn more about Mathis’ research here.

Mathis’ scientific excellence has been recognized by election to the US National Academy of Sciences, the German National Academy of Sciences Leopoldina, and the American Academy of Arts and Sciences.  Mathis is also an active member of the scientific community reviewing for numerous journals, organizing meetings, and teaching. She was chosen as the 2017 recipient of the FASEB Excellence in Science Award.

Diane Mathis received her BSc from Wake Forest University and her PhD from the University of Rochester.  She was a post-doctoral fellow at the Laboratoire de Génétique Moléculaire des Eucaryotes in Strasbourg, France and at Stanford University.

Talks with this Speaker

T Cell Tolerance

When immunological tolerance fails, autoimmune diseases such as diabetes result. Mathis explains how T cell tolerance develops. (Talk recorded in July 2016)

  • Part 1: An Introduction to T Cell Tolerance
    Part 1: An Introduction to T Cell Tolerance
    Audience:
    • Student
    • Researcher
    • Educators of H. School / Intro Undergrad
    • Educators of Adv. Undergrad / Grad
    Duration: 36:39
  • Part 2: Transcription Factor Aire Orchestrates T Cell Tolerance
    Part 2: Transcription Factor Aire Orchestrates T Cell Tolerance
    Audience:
    • Researcher
    • Educators of Adv. Undergrad / Grad
    Duration: 37:23

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This material is based upon work supported by the National Science Foundation and the National Institute of General Medical Sciences under Grant No. 2122350 and 1 R25 GM139147. Any opinion, finding, conclusion, or recommendation expressed in these videos are solely those of the speakers and do not necessarily represent the views of the Science Communication Lab/iBiology, the National Science Foundation, the National Institutes of Health, or other Science Communication Lab funders.

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