Dr. Tsien was a Professor at the University of California, San Diego, a Howard Hughes Medical Institute Investigator and a member of the National Academy of Sciences. In 2008, Tsien shared the Nobel Prize in Chemistry for the discovery and development of green fluorescent protein, GFP. His lab continues to develop new fluorescent proteins as tools to study cell signaling.
Talks with this Speaker
Correlating Fluorescence with Electron Microscopy
Roger Tsien discusses correlating fluorescence with electron microscopy using miniSOG, a protein that can be imaged fluorescently and produces an electron-dense deposit. (Talk recorded in May 2012)
Audience:
- Researcher
- Educators of Adv. Undergrad / Grad
Duration: 8:08
Optimizing Detection of GFP
Roger Tsien discusses how to optimize for detection of GFP, the factors controlling the detectability of GFP within the cell, and how to optimize these factors so as to maximize its detectability. (Talk recorded in May 2012)
Audience:
- Researcher
- Educators of Adv. Undergrad / Grad
Duration: 8:53
Fluorescent Protein Indicators
Roger Tsien discusses fluorescent protein indicators and their use in detecting biological properties including pH and redox potential, as well as their use as signaling molecules. (Talk recorded in May 2012)
Audience:
- Researcher
Duration: 42:00
Fluorescent Proteins and the Story Behind GFP
Roger Tsien describes fluorescent proteins, covers the history of GFP, how GFP folds and becomes fluorescent, and how GFP has been altered to produce additional colors. (Talk recorded in May 2012)
Audience:
- Student
- Researcher
- Educators of Adv. Undergrad / Grad
Duration: 34:36
Fluorescent Proteins and the Story Behind GFP
Live cell imaging has been revolutionized by the discovery of the green fluorescent protein (GFP). (Talk recorded in May 2012)
Audience:
- Student
- Researcher
- Educators of Adv. Undergrad / Grad
Duration: 34:36
