Bonnie Bassler: Cell-Cell Communication in Bacteria

I. Bacterial Communication via Quorum Sensing
II. Vibrio Cholerae Quorum Sensing and Developing Novel Antibiotics

Part I: Cell-Cell Communication in Bacteria

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Lecture Overview
Bacteria, primitive single-celled organisms, communicate with chemical languages that allow them to synchronize their behavior and thereby act as enormous multi-cellular organisms. This process is called quorum sensing and it enables bacteria to successfully infect and cause disease in plants, animals, and humans. Investigations of the molecular mechanisms underlying quorum sensing are leading to the development of novel strategies to interfere with quorum sensing. These strategies form the basis of new therapies to be used as antibiotics.

Speaker Bio
Bonnie Bassler is a member of the National Academy of Sciences and the American Academy of Arts and Sciences. She is a Howard Hughes Medical Institute Investigator and the Squibb Professor of Molecular Biology at Princeton University. Bassler received a B.S. in Biochemistry from the University of California at Davis, and a Ph.D. in Biochemistry from the Johns Hopkins University. More >>

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  1. Lars Nielsen says

    Impressive science and engaging delivery. Your animated style and enthusiasm for the subject on the foundation of dense information and years of proficient experimentation have made these 50 minutes not only arguably the most usefully spent (as has been commented regarding other iBiology talks), but also the most tantalizingly entertaining.

  2. Tyler says

    Hey, i really appreciated this video. I recently have become very intrigued about bacteria. I wonder! so much to learn. i really value how you made it very understandable!

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