Witkin provides a historical perspective on how working at Cold Spring Harbor (CSH) shaped her scientific career and led to the discovery of the SOS DNA damage response in bacteria. At CSH she worked with the pioneers of bacterial genetics, at a time when there was a major discovery every other week. As a PhD student Witkin observed that some bacteria were able to survive high doses of UV radiation. She speculated that these bacteria may have a mechanism to repair DNA making them UV resistant. These revolutionary ideas gave birth to the discovery that cells have a mechanism to repair DNA damage, the SOS response.
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The SOS Response in Bacteria
Witkin provides a historical perspective on how working at Cold Spring Harbor shaped her scientific career and led to the discovery of the SOS DNA damage response in bacteria. (Talk recorded in September 2015)
Audience:
- General Public
- Student
- Researcher
- Educators of H. School / Intro Undergrad
- Educators of Adv. Undergrad / Grad
Duration: 16:17