Evolution has selected wild organisms to be extremely well adapted to their environment. Because most genetic changes introduced by humans divert the resources of the organism to benefit humans, such mutations are typically eliminated by natural selection in the ancestral habitat. In his first talk, Dr. Kevin Esvelt explains how self-propagating CRISPR-based gene drives can be used to spread genetic alterations through wild populations, potentially impacting all organisms of the target species. Gene drives could be used to benefit public health, the environment, agriculture, and animal well-being. However, real-world use may incur ecological risks, and even research involving self-propagating gene drive systems may risk public trust in science and governance given the possibility of accidental spread. Esvelt explains how to minimize risk and discusses the importance of engaging communities in planning any projects which may affect them.
View the full talk with additional resources on our website
Gene Drive
Dr. Kevin Esvelt explains how CRISPR-based gene drives can be used to spread genetic alterations through wild populations. He discusses strategies to maximize benefit and minimize risk. (Talk recorded in July 2018)
- Part 1: Gene DriveAudience:
- Student
- Researcher
- Educators of H. School / Intro Undergrad
- Educators of Adv. Undergrad / Grad
Duration: 00:25:23 - Part 2: Gene Drive and Local DriveAudience:
- Student
- Researcher
- Educators of H. School / Intro Undergrad
- Educators of Adv. Undergrad / Grad
Duration: 00:32:59