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Home » Speakers » Anne Bertolotti
Anne Bertolotti

Anne Bertolotti

MRC Laboratory of Molecular Biology

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Dr. Anne Bertolotti’s research focuses on understanding and preventing the deposition of misfolded proteins in cells, a hallmark of numerous neurological diseases. Bertolotti has been a group leader at the MRC Laboratory of Molecular Biology in Cambridge, UK since 2006. Prior to joining the LMB, she was an Associate Professor at Ecole Normale Superieure in Paris from 2001-2006.  Bertolotti did her PhD training at the Institute of Genetics and Molecular and Cellular Biology (IGBMC) near Strasbourg, France and she was a post-doctoral fellow at the Skirball Institute of Biomolecular Medicine at NYU School of Medicine in New York.

Bertolotti was elected an EMBO Young Investigator in 2005 and an EMBO member in 2013. In 2014, she was awarded the Hooke Medal of the British Society for Cell Biology for her contributions to our understanding of abnormal protein folding.  Bertolotti was elected a Fellow of the UK Academy of Medical Sciences in 2017. Learn more about Bertolotti’s research here.

Talks with this Speaker

Protein Phosphatases

Kinases and phosphatases perform a balancing act in cells by adding and removing phosphate groups from proteins. Dr. Bertolotti shows us that inhibiting specific protein phosphatases can reduce misfolded protein accumulation and reduce neurodegenerative disease. (Talk recorded in January 2019)

  • Part 1: A Historical Perspective on Protein Phosphatases
    Part 1: A Historical Perspective on Protein Phosphatases
    Audience:
    • Student
    • Researcher
    • Educators of H. School / Intro Undergrad
    • Educators of Adv. Undergrad / Grad
    Duration: 00:29:15
  • Part 2: Benefits of Phosphatase Inhibition for Neurodegenerative Diseases
    Part 2: Benefits of Phosphatase Inhibition for Neurodegenerative Diseases
    Audience:
    • Researcher
    • Educators of Adv. Undergrad / Grad
    Duration: 00:30:12
  • Part 3: A Platform to Identify Selective Protein Phosphatase Inhibitors
    Part 3: A Platform to Identify Selective Protein Phosphatase Inhibitors
    Audience:
    • Researcher
    • Educators of Adv. Undergrad / Grad
    Duration: 00:34:15

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This material is based upon work supported by the National Science Foundation and the National Institute of General Medical Sciences under Grant No. 2122350 and 1 R25 GM139147. Any opinion, finding, conclusion, or recommendation expressed in these videos are solely those of the speakers and do not necessarily represent the views of the Science Communication Lab/iBiology, the National Science Foundation, the National Institutes of Health, or other Science Communication Lab funders.

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