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Home » Speakers » Michael Brown
Michael Brown

Michael Brown

University of Texas Southwestern Medical Center
Canada Gairdner Award Lasker Award National Medal of Science Nobel Prize

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Michael S. Brown received a B.A. degree in Chemistry in 1962 and an M.D. degree in 1966 from the University of Pennsylvania. He was an intern and resident at the Massachusetts General Hospital, and a postdoctoral fellow with Dr. Earl Stadtman at the National Institutes of Health. In 1971, he came to UT Southwestern where he rose through the ranks to become a professor in 1976. He is currently Paul J. Thomas Professor of Molecular Genetics and Director of the Jonsson Center for Molecular Genetics at UT Southwestern.

Dr. Brown and his long-time colleague, Dr. Joseph L. Goldstein, together discovered the low density lipoprotein (LDL) receptor, which controls the level of cholesterol in blood and in cells. They showed that mutations in this receptor cause Familial Hypercholesterolemia, a disorder that leads to premature heart attacks in one out of every 500 people in most populations. They have received many awards for this work, including the U.S. National Medal of Science and the Nobel Prize for Medicine or Physiology.

Talks with this Speaker

Nobel Prize - Collaboration in Science

Nobel Prize – Collaborations: The Nobel Prize is about rewarding the work of individuals. We talked to four Nobel Laureates about their thoughts on collaboration in science. (Talk recorded in October 2016)

Audience:
  • General Public
  • Student
  • Researcher
  • Educators of H. School / Intro Undergrad
  • Educators of Adv. Undergrad / Grad
Duration: 02:20

When Stockholm Called

We asked 12 Nobel Laureates to tell us their story of when Stockholm called. (Talk recorded in September 2016)

When Stockholm Called
Audience:
  • General Public
  • Student
  • Researcher
  • Educators of H. School / Intro Undergrad
  • Educators of Adv. Undergrad / Grad
Duration: 2:42

Familial Hypercholesterolemia

Joe Goldstein and Michael Brown identified the basis of familial hypercholesterolemia (FH), a disease characterized by high LDL cholesterol and atherosclerosis. (Talk recorded in August 2014)

  • Part 1: The Molecular Basis of Familial Hypercholesterolemia
    Part 1: The Molecular Basis of Familial Hypercholesterolemia
    Audience:
    • General Public
    • Student
    • Researcher
    • Educators of H. School / Intro Undergrad
    • Educators of Adv. Undergrad / Grad
    Duration: 20:18
  • Part 2: The Joys of Collaboration
    Part 2: The Joys of Collaboration
    Audience:
    • General Public
    • Student
    • Researcher
    • Educators of H. School / Intro Undergrad
    • Educators of Adv. Undergrad / Grad
    Duration: 6:54

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This material is based upon work supported by the National Science Foundation and the National Institute of General Medical Sciences under Grant No. 2122350 and 1 R25 GM139147. Any opinion, finding, conclusion, or recommendation expressed in these videos are solely those of the speakers and do not necessarily represent the views of the Science Communication Lab/iBiology, the National Science Foundation, the National Institutes of Health, or other Science Communication Lab funders.

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