In an interview with Ron Vale, Ian Gibbons describes how his initial chemical dissection of the internal structure of Tetrahymena cilia led him to seek and then identify the force-producing ATPase, which he named dynein. Gibbons also describes his key experiment showing that dynein produces sliding between microtubules, which gives rise to the beating of cilia and flagella, as well as his more recent experiments aimed at understanding dynein’s motility mechanism at an atomic level.
Ian Gibbons, together with his wife Barbara, identified and named the motor protein dynein. Gibbons has continued to work on the function and structure of dynein throughout his long career. After receiving his PhD in biophysics from the University of Cambridge, he took a position at Harvard and then at the Kewalo Marine Laboratory at… Continue Reading