Proteins such as signaling molecules, catalytic enzymes, and membrane transporters are not static but are in a state of constant motion for function. In her first talk, Dorothee Kern explains how she uses techniques such as nuclear magnetic resonance (NMR), X ray crystallography, single molecule FRET and computational simulations to visualize rapid protein dynamics. Kern walks us through the basics of these techniques and explains how they can provide structural and energetic information about a protein and how it functions in the cell.
View the full talk with additional resources on our website
Visualizing Protein Dynamics
Dorothee Kern explains how visualizing protein dynamics (i.e. watching proteins in action) allows us to better understand protein function and optimize drug design. (Talk recorded in July 2017)
- Part 1: Visualizing Protein DynamicsAudience:
- Student
- Researcher
- Educators of H. School / Intro Undergrad
- Educators of Adv. Undergrad / Grad
Duration: 38:33 - Part 2: Using Evolution to Reveal a Cancer Drug’s MechanismAudience:
- Researcher
- Educators of Adv. Undergrad / Grad
Duration: 29:51