Many animals are able to regenerate following injury, some better than others. Dr. Reddien uses Planaria as a model system to investigate the cellular and molecular mechanisms that drive regeneration. RNAi makes it possible to inhibit specific genes in Planaria and follow the effects on protein expression and regeneration. Using this methodology, Reddien’s lab identified the notum gene as a regulator of the wnt signaling pathway for determining appropriate head or tail regeneration.
View the full talk with additional resources on our website
Molecular Mechanisms that Drive Regeneration
Peter Reddien discusses using planaria to investigate the cellular and molecular mechanisms that drive regeneration. (Talk recorded in February 2013)
Audience:
- Researcher
- Educators of Adv. Undergrad / Grad
Duration: 27:18