Lupus is a disease in which the immune system becomes erroneously activated and attacks a patient’s own tissues. Using a mouse model of lupus called Rasgrp1, Dr. Darienne Myers investigates the molecular mechanisms of this autoimmune disease. Specifically, she asks how the immune system knows when to mount a response. She discovers increased levels of mTOR (Target of Rapamycin) signaling and protein translation in the Rasgrp1 mouse’s T cells, which contributes to the lupus-like disease displayed by the animal.
This talk is part of the Young Scientist Seminars, a video series produced that features young scientists giving talks about their research and discoveries.
Darienne Myers received her Bachelor’s Degree in Biology from Amherst College. After this, she worked as a research assistant in Dr. Fred Alt’s lab in Boston, MA, where she first became excited by Immunology research. Darienne then pursued a Ph.D. in Biomedical Sciences with a focus in Immunology at the University of California, San Francisco… Continue Reading