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Home » Educator Resources » Seminars with Teaching Tools » Broken Chromosome Repair by Homologous Recombination

Broken Chromosome Repair by Homologous Recombination

Broken chromosomes naturally arise during DNA replication. In healthy cells, the breaks are repaired by homologous recombination. If the repair machinery is broken, cancer can result.

With: James Haber

Broken Chromosome Repair by Homologous Recombination: James Haber
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Broken Chromosome Repair by Homologous Recombination Broken Chromosome Repair by Homologous Recombination
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Double-strand breaks (DSBs), mechanisms of homologous recombination, genome stability 00:35:59 Hi-Res Low-Res

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Molecular Mechanisms of Repairing a Broken Chromosome  Molecular Mechanisms of Repairing a Broken Chromosome
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DNA double-strand break repair 00:33:14 Hi-Res Low-Res

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Mutations Arising during Repair of a Broken Chromosome Mutations Arising during Repair of a Broken Chromosome
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Mistakes in homologous recombination repair, base pair substitutions, frame shifts mutations 00:23:01 Hi-Res Low-Res

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Funders

NSF
NIGMS
Lasker
Rita Allen

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This material is based upon work supported by the National Science Foundation and the National Institute of General Medical Sciences under Grant No. 2122350 and 1 R25 GM139147. Any opinion, finding, conclusion, or recommendation expressed in these videos are solely those of the speakers and do not necessarily represent the views of the Science Communication Lab/iBiology, the National Science Foundation, the National Institutes of Health, or other Science Communication Lab funders.

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