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Home » Speakers » Cynthia Kenyon
Cynthia Kenyon

Cynthia Kenyon

Calico
National Academy of Sciences

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Cynthia Kenyon graduated valedictorian in chemistry and biochemistry from the University of Georgia in 1976. She received her PhD from MIT in 1981, where, in Graham Walker’s laboratory, she was the first to look for genes on the basis of their expression profiles, discovering that DNA damaging agents activate a battery of DNA repair genes in E. coli.

She then did postdoctoral studies with Nobel laureate Sydney Brenner at the MRC Laboratory of Molecular Biology in Cambridge, UK, studying the development of C. elegans. Since 1986 she has been at the University of California, San Francisco, where she was the Herbert Boyer Distinguished Professor of Biochemistry and Biophysics and is now an American Cancer Society Professor.

In 1993, Kenyon and colleagues’ discovery that a single-gene mutation could double the lifespan ofC. elegans sparked an intensive study of the molecular biology of aging. These findings have now led to the discovery that an evolutionarily conserved hormone signaling system controls aging in other organisms as well, including mammals. Dr. Kenyon has received many honors and awards for her findings.

She is a member of the US National Academy of Sciences, the American Academy of Arts and Sciences, and the Institute of Medicine and she is a past president of the Genetics Society of America. She is now the director of the Hillblom Center for the Biology of Aging at UCSF.

Talks with this Speaker

A Genetic Control Circuit for Aging

In her talk about discovering a genetic control circuit for aging, Cynthia Kenyon describes how a single gene mutation causes C. elegans to live twice as long as normal. (Talk recorded in October 2012)

Cynthia Kenyon (UCSF): A Genetic Control Circuit for Aging
Audience:
  • General Public
  • Student
  • Researcher
  • Educators of H. School / Intro Undergrad
  • Educators of Adv. Undergrad / Grad
Duration: 10:20

Aging Genes: Genes and Cells that Determine the Lifespan of the Nematode C. elegans

Dr. Cynthia Kenyon explains that by manipulating aging genes in the nematode C. elegans, they can lengthen lifespan up to 6 fold. (Talk recorded in May 2007)

  • Part 1: Genes that Control Aging
    Part 1: Genes that Control Aging
    Audience:
    • General Public
    • Student
    • Researcher
    • Educators of H. School / Intro Undergrad
    • Educators of Adv. Undergrad / Grad
    Duration: 42:46
  • Part 2: Regulation of Aging by Signals from the Reproductive System
    Part 2: Regulation of Aging by Signals from the Reproductive System
    Audience:
    • Researcher
    • Educators of Adv. Undergrad / Grad
    Duration: 37:16

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This material is based upon work supported by the National Science Foundation and the National Institute of General Medical Sciences under Grant No. MCB-1052331. Any opinion, finding, conclusion, or recommendation expressed in these videos are solely those of the speaker and do not necessarily represent the views of iBiology, the National Science Foundation, the National Institutes of Health, or other iBiology funders.

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