Doug Koshland is the Richard and Rhoda Goldman Distinguished Chair in the Biological Sciences & Professor of Genetics, Genomics and Development at University of California, Berkeley. His laboratory uses budding yeast to study the fundamental processes of higher order chromosome structure, the maintenance of genome integrity, and stress tolerance. Specifically, his approach has been to develop novel genetic reagents and cell biological methods to analyze these complex processes in vivo, coupled with the development of in vitro assays to reveal underlying molecular mechanisms. Doug earned his B.A. in Chemistry from Haverford College and his Ph.D. in microbiology from Massachusetts Institute of Technology under the guidance of David Botstein. He then did his postdoctoral work with Leland Hartwell at University of Washington and with Marc Kirschner at the University of California, San Francisco. He was a staff scientist at Carnegie Institution for Science from 1987 and an adjunct professor in the Department of Biology at Johns Hopkins University. He was a Howard Hughes Medical Institute (HHMI) investigator from 1997-2012, was inducted into the National Academy of Science in 2010, and is a Fellow of the American Association for the Advancement of Science.