Dr. Hans Clevers is a Principal Investigator at the Hubrecht Institute, a Professor in Molecular Genetics at the University Medical Center Utrecht, and an Oncode Investigator. He obtained his medical (1984) and doctoral (1985) degrees at the University of Utrecht. He continued his education as a post-doctoral fellow in the lab of Dr. Cox Terhorst at the Dana-Farber Cancer Institute at Harvard Medical School. In 1989, he joined the faculty at the University of Utrecht, where his lab studies the biology of Wnt signaling in development and cancer. Using Lgr5 as a marker, his lab discovered adult stem cells in the intestine, and developed a technique to grow these stem cells into epithelial organoids. Using these organoids, his lab is able to study a multitude of physiological, and pathological processes, and use organoids as a model to understand disease progression and predict drug responses.
For his scientific contributions, Clevers received the Breakthrough Prize in Life Sciences in 2013, and is an elected member of the European Molecular Biology Organization (EMBO) (1999), the Royal Netherlands Academy of Sciences (2000), the National Academy of Sciences (2014), the French Academie des Sciences (2017) and the Royal Society of London (2019). Visit his lab website and learn more about Clevers’ research.