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Home » Speakers » James Spudich
James Spudich

James Spudich

Stanford University
Lasker Award National Academy of Sciences

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James Spudich is the Douglass M. and Nola Leishman Professor of Cardiovascular Disease in the Department of Biochemistry at Stanford University School of Medicine.  For the past several decades, his lab has studied the structure and function of the myosin family of motor proteins.  More recently Spudich’s lab has focused on human cardiac muscle myosin and the molecular basis of hypertrophic cardiomyopathy.  

Spudich received his B.S. in chemistry from the University of Illinois and his Ph.D. in biochemistry from Stanford University. He was a postdoctoral fellow at Stanford University and then at the MRC Laboratory in Cambridge where he worked with Hugh Huxley.  Spudich joined the faculty of the University of California, San Francisco from 1971-1977.  In 1977, he moved to Stanford University where he was first a professor in the Department of Structural Biology and, since 1992, has been a professor in the Department of Biochemistry.  Spudich is also an Adjunct Professor at the Institute of Stem Cell Biology and Regenerative Medicine (inStem) and the National Center for Biological Sciences (NCBS) in Bangalore, India.

Spudich serves on numerous editorial and scientific advisory boards.  His research contributions have been recognized with many honors and prizes including the Albert Lasker Basic Medical Research Award in 2012, the E.B. Wilson Award from the American Society for Cell Biology in 2011, and the Biophysics Society Award for Outstanding Investigator in 2005.  He is an elected fellow of the American Association for the Advancement of Science and the American Academy of Arts and Sciences, and an elected member of the US National Academy of Sciences. 
Learn more about Spudich’s research here.

Talks with this Speaker

A Brief History of Muscle Biology

James Spudich begins his talk with an early history of muscle biology and moves forward to our current understanding of the molecular basis of muscle contraction and disease. (Talk recorded in May 2017)

  • Part 1: A Brief History of Muscle Biology 1864-1969
    Part 1: A Brief History of Muscle Biology 1864-1969
    Audience:
    • Student
    • Researcher
    • Educators of H. School / Intro Undergrad
    • Educators of Adv. Undergrad / Grad
    Duration: 31:05
  • Part 2: A Brief History of Muscle Biology 1969-2017
    Part 2: A Brief History of Muscle Biology 1969-2017
    Audience:
    • Student
    • Researcher
    • Educators of H. School / Intro Undergrad
    • Educators of Adv. Undergrad / Grad
    Duration: 31:32
  • Part 3: Ca 2+ Regulation of Muscle Contraction
    Part 3: Ca 2+ Regulation of Muscle Contraction
    Audience:
    • Researcher
    • Educators of Adv. Undergrad / Grad
    Duration: 32:23
  • Part 4: Myosin Mutations and Hypertrophic Cardiomyopathy
    Part 4: Myosin Mutations and Hypertrophic Cardiomyopathy
    Audience:
    • Researcher
    • Educators of Adv. Undergrad / Grad
    Duration: 37:56

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Funders

NSF
NIGMS
Lasker
Rita Allen

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This material is based upon work supported by the National Science Foundation and the National Institute of General Medical Sciences under Grant No. 2122350 and 1 R25 GM139147. Any opinion, finding, conclusion, or recommendation expressed in these videos are solely those of the speakers and do not necessarily represent the views of the Science Communication Lab/iBiology, the National Science Foundation, the National Institutes of Health, or other Science Communication Lab funders.

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