Two pioneering electron microscopists, John Heuser and Tom Reese, reminisce about their early experiments to understand synaptic vesicle transmission. They describe the development of freeze fracture electron microscopy, a technique that allowed them, for the first time, to image events at the nerve terminal just milliseconds after stimulation.
In their second talk, Heuser and Reese explain why they are still enthusiastic about the future of electron microscopy even in the age of “super-resolution” light microscopy.
And, in their third talk, Reese and Heuser explain why they have remained close friends and collaborators for years, despite occasionally fighting like cats and dogs.
Tom Reese is a Senior Investigator at the National Institute of Neurological Diseases and Stroke at the National Institutes of Health and a summer researcher at the Marine Biological Laboratory. He continues to study synaptic structure and function using advanced light and electron microscopy techniques. Reese was elected to the National Academy of Sciences in… Continue Reading
John Heuser is a Professor Emeritus in Cell Biology and Physiology at Washington University in St. Louis. Heuser developed and spent his career using quick-freeze, deep-etch electron microscopy to study all aspects of cell biology. In recognition of his work, Heuser was elected to the National Academy of Sciences in 2011. Learn more about Dr…. Continue Reading