Paul Berg tells Larry Goldstein how concerns about an early recombinant DNA experiment in his lab launched him into the science policy arena. He describes organizing the 1975 Asilomar Conference on Recombinant DNA and promoting guidelines that aimed to ensure the safety of recombinant DNA technology. Both the guidelines and the meeting format continue to impact science policy today.
Larry Goldstein is Professor of Cellular and Molecular Medicine at the University of California, San Diego and a Howard Hughes Medical Institute Investigator. Goldstein is also a recipient of the ASCB Public Service Award. The Goldstein lab studies how molecular motors interact with axonal vesicles and how this relates to neurodegenerative disease such as Alzheimer’s… Continue Reading
Paul Berg joined the nascent Biochemisty department at Stanford University in 1959 and has remained there since. Berg’s early work led to the discovery of the aminoacyl tRNA synthetases and tRNAs and their role in protein synthesis. Berg was a pioneer in developing recombinant DNA techniques, work for which he shared the 1980 Nobel Prize… Continue Reading