In Part 1 of his lecture, Tjian gives an overview of the complex and critical role that transcription factors play in regulating gene expression. How do different cells from the same organism, such as muscle cells, neurons and red blood cells, all of which have identical DNA, have such different phenotypes? Tjian addresses this question in his second lecture, where he expands on the mechanisms of gene regulation.
Robert Tjian has been President of the Howard Hughes Medical Institute since 2009. He is also a professor of biochemistry and molecular biology at the University of California, Berkeley where he maintains a research lab focused on understanding the regulation of gene expression. Tjian received his bachelor’s degree in biochemistry from UC Berkeley and his… Continue Reading